Speech, Language, and Oromotor Skills in Patients With Polymicrogyria

RO Braden; JO Boyce; CA Stutterd; K Pope; H Goel; RJ Leventer; IE Scheffer; AT Morgan

Journal article

Speech, Language, and Oromotor Skills in Patients With Polymicrogyria

RO Braden, JO Boyce, CA Stutterd, K Pope, H Goel, RJ Leventer, IE Scheffer, AT Morgan

Neurology | LIPPINCOTT WILLIAMS & WILKINS | Published : 2021

DOI: 10.1212/WNL.0000000000011698

Abstract

Objective To determine whether specific speech, language, and oromotor profiles are associated with different patterns of polymicrogyria, we assessed 52 patients with polymicrogyria using a battery of standardized tests and correlated findings with topography and severity of polymicrogyria.MethodsPatients were identified via clinical research databases and invited to participate, irrespective of cognitive and verbal language abilities. We conducted standardized assessments of speech, oromotor structure and function, language, and nonverbal IQ. Data were analyzed according to normative assessment data and descriptive statistics. We conducted a correlation analysis between topographic pattern ..

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University of Melbourne Researchers

Jessica Boyce Author

Rick Leventer Author

Ingrid Scheffer Author

Angela Morgan Author

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Grants

Awarded by Murdoch Children's Research Institute

Funding Acknowledgements

R.O.B. is supported by a National Health and Medical Research Council (NHMRC) Centre of Research Excellence PhD stipend in Speech and Language Neurobiology (ID 1116976), awarded to A.T.M. and I.E.S. The study is also supported by NHMRC Practitioner Fellowships awarded to A.T.M. (1105008) and I.E.S. (1104831), project grant 1127144 awarded to A.T.M., and program grant 1091593 awarded to I.E.S. R.O.B. is supported by a Nadia Verrall Memorial Research Grant awarded by Speech Pathology Australia and a Postgraduate Health Research Scholarship awarded by the Murdoch Children's Research Institute. R.J.L. is supported by a Melbourne Children's Clinician Scientist Fellowship. C.A.S. was supported by the Flora Suttie Neurogenetics Fellowship and the Campbell Edwards Trust. This work was supported by the Victorian Government's Operational Infrastructure Support Program and Australian Government NHMRC Independent Research Institute Infrastructure Support Scheme.